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Archive for the ‘Clinical Trials / Drug Trials’ Category

PharmaLive: Advanced Life Sciences Announces Collaboration With UK Ministry of Defence on ALS-886

Thursday, July 17th, 2008

CHICAGO, July 17, 2008 /PRNewswire-FirstCall/ -- Advanced Life Sciences Holdings, Inc. , today announced that the United Kingdom's Defence Science and Technology Laboratory ("Dstl") will evaluate the developmental compound ALS-886 as a treatment for chemically induced lung injury. ALS-886 is a small molecule therapeutic that, in preclinical studies, has demonstrated ...

PharmaLive: BioNumerik Pharmaceuticals Observes Evidence of a Survival Increase in Lung Cancer Patients Participating in Tavocept Clinical Trial

Thursday, July 17th, 2008

- Second instance where survival increase is observed in advanced non-small cell lung cancer patients receiving Tavocept in conjunction with standard chemotherapySAN ANTONIO, July 17, 2008 /PRNewswire/ -- BioNumerik Pharmaceuticals, Inc. ("BioNumerik") today announced that patients with adenocarcinoma (the most frequently occurring form of lung cancer) participating in a Phase ...

PharmaLive: Bradmer Reports Progression Free Survival Data from Previous Phase II Glioblastoma Multiforme Trials

Thursday, July 17th, 2008

TORONTO, July 17, 2008 /PRNewswire-FirstCall/ - Bradmer Pharmaceuticals Inc. , a biopharmaceutical company dedicated to the development and commercialization of cancer therapies, today released progression free survival (PFS) data from two previously conducted Phase II trials of Neuradiab(TM) in glioblastoma multiforme (GBM) patients. As an exploratory endpoint of the single ...

PharmaLive: Introgen to Present ADVEXIN Phase 3 Study Results at American Association for Cancer Research’s Cancer Clinical Trials and Personalized Medicine Conference

Thursday, July 17th, 2008

Supplemental Statistical Analysis Supports Superior Efficacy of ADVEXIN in p53 Biomarker Patient PopulationAUSTIN, Texas--(BUSINESS WIRE)--July 17, 2008--Introgen Therapeutics, Inc. (NASDAQ:INGN), a developer of targeted molecular therapies for cancer, today announced that the company will present the results from its recently completed Phase 3 trial of ADVEXIN in recurrent head and ...

PharmaLive: Vical Announces Breakthrough for Pandemic Influenza DNA Vaccines With Preliminary Human Data

Thursday, July 17th, 2008

SAN DIEGO, July 17, 2008 /PRNewswire-FirstCall/ -- Vical Incorporated today announced a breakthrough with preliminary clinical trial data demonstrating that DNA vaccines can safely achieve significant immune responses against H5N1 pandemic influenza in humans. DNA vaccines are fundamentally different from conventional vaccines because they do not contain any part of ...

PharmaLive: Biojector 2000 Data Presented in Vical’s Pandemic Influenza DNA Vaccine Human Trial

Thursday, July 17th, 2008

PORTLAND, Ore.--(BUSINESS WIRE)--Jul 17, 2008 - Bioject Medical Technologies Inc. (Nasdaq: BJCT), a leading developer of needle-free injection therapy systems, today announced that the Biojector(R) 2000 (B2000) was used in Vical Inc.'s (Vical) first Phase 1 human trial of H5N1 pandemic influenza DNA vaccines formulated with Vical's Vaxfectin(R) adjuvant. Data ...

PharmaLive: Biodel Inc. Announces the Completion of Its Two Pivotal Trials and the Release of EASD Abstracts Containing Additional Interim Data From Its VIAject Program

Thursday, July 17th, 2008

DANBURY, Conn., July 16, 2008 /PRNewswire-FirstCall/ -- Biodel Inc. today announced that its two pivotal Phase III VIAject(TM) clinical trials are now complete, with the last study patient visit on July 14, 2008. Results of the full trial will be released either at Biodel's poster presentation at the European Association ...

PharmaLive: Published Study Demonstrates Lower Serum Creatinine Levels after Contrast Media Administration with Iodixanol Than with Iopromide

Thursday, July 17th, 2008

PRINCETON, N.J.--(BUSINESS WIRE)--Jul 16, 2008 - GE Healthcare's iodixanol, an isosmolar contrast medium, shows lower incidence of elevated serum creatinine (SCr) or decreased glomerular filtration rate (GFR) than iopromide, concluded a study written by a team of physicians and researchers at the Medical University of South Carolina, and published in ...

PharmaLive: Repros Therapeutics Inc. Announces That Proellex Administered to Patients as Cyclic Therapy to Treat the Symptoms of Uterine Fibroids for Up to 30 Months Shows No Adverse Effects on the Endometrium

Thursday, July 17th, 2008

THE WOODLANDS, Texas--(BUSINESS WIRE)--July 16, 2008 - Repros Therapeutics Inc. (NasdaqGM:RPRX) today released strong results from its completed extension safety study of Proellex in the chronic treatment of the symptoms associated with uterine fibroids. To date there have been no abnormal histological findings from the endometrial biopsies taken post menses ...

PharmaLive: MaxCyte to Present Scalable Clinical and Commercial Manufacturing Technology for Cell-based and Viral-based Vaccines

Thursday, July 17th, 2008

GAITHERSBURG, Md., July 16 /PRNewswire/ -- MaxCyte, Inc., a clinical-stage therapeutics company and pioneer in clinical scale, non-viral cell loading systems, announces that Madhusudan V. Peshwa, Ph.D., Vice President Research and Development at MaxCyte, will present on Thursday, July 17, 2008 at 4:40PM EDT at IBC's Next Generation Vaccines Conference ...

PharmaLive: Insightful Corporation Announces Webinar on “Graphical Evaluation for Cardiovascular Safety Data in Clinical Trials”

Thursday, July 17th, 2008

SEATTLE--(BUSINESS WIRE)--Jul 16, 2008 - Insightful Corporation (NASDAQ:IFUL), a leading provider of predictive analytics and reporting solutions, announced today the company will host a free webinar titled "Graphical Evaluation for Cardiovascular Safety Data in Clinical Trials" on July 17, 2008 from 8:30 to 9:30 a.m., Pacific Daylight Time. Dr. Ihab ...

PharmaLive: URGENT Study Provides Important New Insight into the Use of Dyspnea as a Clinical Endpoint for Evaluating New Treatments for Acute Heart Failure Syndromes

Wednesday, July 16th, 2008

BEDMINSTER, N.J.--(BUSINESS WIRE)--Jul 16, 2008 - EKR Therapeutics, Inc., a specialty pharmaceutical company focused on providing novel products for the acute-care hospital setting, today said that its prospective, observational study of heart failure patients showed that early evaluation of dyspnea (shortness of breath) is crucial in assessing patients with acute ...

PharmaLive: MIV Provides Update on Its Next-Generation, Ultra-Thin Protea Stent Platform

Wednesday, July 16th, 2008

ATLANTA--(BUSINESS WIRE)--Jul 16, 2008 - MIV Therapeutics, Inc. (OTCBB:MIVI) (Frankfurt:MIVN), a leading developer of next-generation coatings and advanced drug-delivery systems for cardiovascular stents and other implantable medical devices, today announced that its Protea(TM) ultra-thin cobalt-alloy bare metal stent has excelled in animal studies. The Protea is the Company's next generation ...

PharmaLive: Optimer Pharmaceuticals Announces Positive Results in Prulifloxacin Phase 3 Study

Wednesday, July 16th, 2008

SAN DIEGO--(BUSINESS WIRE)--July 16, 2008 - Optimer Pharmaceuticals, Inc. (Nasdaq:OPTR) today announced positive results from its first double-blind Phase 3 trial assessing the safety and efficacy of Prulifloxacin as a once-daily (600 mg), three-day oral therapy for infectious diarrhea. The top-line analysis of data from this study shows that Prulifloxacin ...

PharmaLive: Inovio Biomedical’s First Proprietary DNA Vaccine Achieves 100% Protection Against Avian Flu in Pre-Clinical Testing

Wednesday, July 16th, 2008

SAN DIEGO--(BUSINESS WIRE)--July 16, 2008 - Inovio Biomedical Corporation (AMEX:INO), a leader in enabling the development of DNA vaccines using a proprietary electroporation-based DNA delivery platform, announced today pre-clinical results from two proprietary plasmid DNA-based universal influenza vaccine candidates using the company's proprietary electroporation delivery technology and, specifically, a new ...