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Archive for the ‘GastroIntestinal / Gastroenterology’ Category

The Accuracy Of CT And MRI In Paraaortic Lymphadenectomy

Thursday, May 22nd, 2008

Paraaortic lymph node metastasis in patients with pancreatico-biliary carcinoma has been reported as a definite predictor of early recurrence and shorter survival term.This study, performed by a team led by Professor Mi-Suk Park and Dr Young Chul Kim, is described in a research article published in the World Journal of ...

A Potential Route For Human Tumor Gene Therapy

Thursday, May 22nd, 2008

The type 1 Na+/H+ exchanger (NHE1) is a transmembrane protein found in all eukaryotic cells. One of its functions is to evacuate excessive H+ in the cytoplasm by means of Na+-H+ exchange, resulting in stable intracellular pH value. Inhibition of the upregulation of NHE-1 gene expression in human gastric carcinoma ...

How To Diagnose And Treat Gardner Syndrome With Gastric Polyposis

Thursday, May 22nd, 2008

Gardner syndrome (GS) is a rare, autosomal, dominant inherited disorder with a high degree of penetrance characterized by the triad: intestinal polyposis and various bone and soft-tissue tumors. It is regarded as a clinical subgroup of familial adenomatous polyposis (FAP).This case, reported by a team led by Dr. Shi-Lin ...

HUMIRA Improves Remission In Crohn’s Patients

Thursday, May 22nd, 2008

An open-label extension study of the CHARM and GAIN studies, performedin Abbott labs, demonstrate that patients with moderate-to-severeCrohn's disease who are treated with HUMIRA®(adalimumab) actually achieved long-term clinical remission and a fullclinical response respectively. This information was presented on May21, 2008 at Digestive Disease Week® (DDW) in San Diego. DDW ...

Improved Treatment For Patients With Portal Hypertension

Thursday, May 22nd, 2008

Bleeding from ruptured esophageal varices is the main complication of portal hypertension and a major cause of death. About one-third of variceal bleeding episodes are fatal while 70% of survivors re-bleed within a year. Propranolol, the drug of choice for primary prevention of variceal bleeding, has been found to be ...

Early Detection And Survival For Pancreatic Cancer Improved By New Research

Wednesday, May 21st, 2008

New research presented at Digestive Disease Week® 2008 (DDW®) showcases innovative methods to better understand the risk factors for and improve earlier detection of pancreatic cancer. Specifically, researchers will demonstrate that the development of, new biomarkers, novel treatment targets, innovative approaches to screening and surveillance and improved understanding of risk ...

New Immunological Drugs Pose Threat Of Infection

Wednesday, May 21st, 2008

A new survey cautions physicians that drugs commonly prescribed for patients suffering from immunological disorders such as rheumatoid arthritis and inflammatory bowel disease may carry risks of serious infections other than the known risk of tuberculosis. The survey published is in the June 1 issue of Clinical Infectious Diseases, currently ...

Superiority Of Ablation Therapy Using HALO System Demonstrated For Eradicating Barrett’s Esophagus And Reducing Risk For Disease Progression

Wednesday, May 21st, 2008

BARRX Medical, Inc., a technology leader in the design and manufacture of medical devices for digestive diseases, today announced the presentation of a landmark study entitled, "A Randomized, Multicenter, Sham-Controlled Trial of Radiofrequency Ablation (RFA) for Subjects with Barrett's Esophagus (BE) Containing ...

New Technology May Mean Immediate Diagnosis For Patients With GI Diseases

Tuesday, May 20th, 2008

A new real-time microscopic technique could change the way gastrointestinal diseases are detected. Research presented at Digestive Disease Week® 2008 (DDW®) shows that confocal laser endomicroscopy (CLE) effectively and immediately identifies suspicious patterns and precancerous cells and may eliminate the need in many cases for biopsy to diagnose gastrointestinal conditions. ...

Potential New Roles For NSAID Medications

Tuesday, May 20th, 2008

Recently, researchers have begun looking to NSAIDs as having a potential role in the prevention of colorectal cancer, esophageal cancer and pancreatitis. Three studies presented at Digestive Disease Week® 2008 (DDW®) investigate the potentially beneficial role that NSAID medications can play in the treatment of GI-related cancer and in the ...

Salix Pharmaceuticals Receives Approvable Letter From FDA For Balsalazide Tablet

Tuesday, May 20th, 2008

Salix Pharmaceuticals, Ltd. (NASDAQ:SLXP) announced that the Company has received an approvable letter from the U.S. Food and Drug Administration (FDA) for balsalazide tablet studied as a treatment of mild-to-moderate active ulcerative colitis in patients 18 years and older. "Late this afternoon Salix received a communication from the FDA that ...

Recurring Symptoms Experienced By Nearly 40 Percent Of GERD Patients Taking PPIs

Monday, May 19th, 2008

Despite daily use of doctor-recommended proton pump inhibitors (PPIs) to control gastroesophageal reflux disease (GERD) symptoms, nearly 40 percent of patients who take them continue to experience breakthrough, which is a return of GERD symptoms, such as acid regurgitation and heartburn. These breakthrough symptoms lead more than half of GERD ...

American College Of Gastroenterology And Npg Announce A New Publishing Partnership

Sunday, May 18th, 2008

The American College of Gastroenterology (ACG) and Nature Publishing Group (NPG) are pleased to announce a new publishing partnership. From January 2009, NPG will publish American Journal of Gastroenterology, the official publication of the ACG. Established in 1934, The American Journal of Gastroenterology is the number ...

New NICE Guidelines Mean IBS Sufferers Will Be Tested For Coeliac Disease, UK

Thursday, May 15th, 2008

The symptoms of IBS and coeliac disease can often be very similar as a result the diagnosis of coeliac disease can be delayed or missed and IBS is misdiagnosed. The new guidelines regarding the diagnosis of Irritable Bowel Syndrome (IBS) announced recently by the National Institute for Health and Clinical ...

454 Sequencing For The Characterization Of The Protective Intestinal Flora

Thursday, May 15th, 2008

The diversity of species in the intestinal flora is imperative for the maintenance of our health. Any instability can lead to the development of various intestinal diseases such as antibiotic-associated intestinal inflammations like e.g., Morbus Crohn or Colitis Ulcerosa. According to the latest discoveries, disturbances in the metabolism such as ...