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Archive for the ‘Lymphoma / Leukemia’ Category

Study Provides Key Safety Data For Human Trials

Thursday, May 15th, 2008

A new study by UC Davis researchers provides evidence that methods using human bone marrow-derived stem cells to deliver gene therapy to cure diseases of the blood, bone marrow and certain types of cancer do not cause the development of tumors or leukemia. The study was published online in the ...

How Cells Communicate To Activate The Cell Division Machinery May Address Problem Of Proliferation Of Malignant Cells And Tumor Growth

Thursday, May 15th, 2008

A study performed by researchers at the Institute for Research in Biomedicine (IRB Barcelona) on the fruit fly, Drosophila melanogaster, unveils how distinct signaling pathways operate between neighboring cells in order to activate the cell proliferation machinery that results in the organized growth of the fly wing. The signaling pathways ...

Non Hodgkin Lymphoma Is Focus Of Cancer In Iowa Report

Sunday, April 6th, 2008

Non-Hodgkin lymphoma is one of the most rapidly increasing types of cancer diagnosed in the United States with new diagnoses having more than doubled since the 1970s. However, over the past 10 years, mortality rates have begun to decline, indicating that progress is being made in its treatment.According to the ...

Leukaemia Research And Argos Celebrate 500,000 Pounds Milestone, UK

Monday, March 31st, 2008

Leukaemia Research is celebrating having raised £500,000 in record time, thanks to the support of Argos employees and customers. Just seven months into the year-long charity partnership, Argos have raised enough funds to support a special cytogenetic database, which will record symptoms and treatments of different types of blood cancer ...

Patients With Non-Hodgkin’s Lymphoma Have Shown Improved Outlook In Last Decade

Friday, March 28th, 2008

Since the 1990s, the survival rates for patients with non-Hodgkinlymphoma (NHL) appear to have increased, according to a reportpublished in the March 10 issue of the Archives of InternalMedicine, one of the JAMA/Archives journals. Non-Hodgkin's lymphoma is a set of different cancers of the lymphocytesin the immune system, and they ...

Genzyme Withdraws Bioenvision’s European Filing Of Evoltra(R) In Elderly AML Patients

Friday, March 28th, 2008

Genzyme Corp. (Nasdaq: GENZ) announced the withdrawal of the European application to extend the Evoltra(R) (clofarabine) product label to include the treatment of elderly patients with acute myeloid leukemia (AML). This application and the data on which it was based were filed by Bioenvision, Ltd. before the company was ...

New Research Gives Additional Therapeutic Tools For Even More Effective And Longer Control Of Chronic Myeloid Leukemia

Tuesday, March 25th, 2008

Oregon Health & Science University Cancer Institute researchers have found that an experimental drug known as SGX393 is effective against Gleevec-resistant chronic myeloid leukemia (CML). The results of their study will be published the week of March 24th in the Proceedings of the National Academy of Sciences.Gleevec, the targeted therapy ...

St. Jude Researchers Believe Molecular Science Could Further Improve Leukemia Survival

Monday, March 24th, 2008

The dramatic increase that has occurred in the cure rate for children with acute lymphoblastic leukemia (ALL) will be difficult to replicate in older patients without considerable additional research, according to an article by St. Jude Children's Research Hospital authors that appears in the March 22 issue of the Lancet.In ...

Bioenvision Ltd Withdraws Its Application For An Extension Of Indication For Evoltra (clofarabine) - Europe

Thursday, March 20th, 2008

The European Medicines Agency (EMEA) has been formally notified by Bioenvision Ltd, a whollyowned subsidiary of Genzyme Corporation, of its decision to withdraw its application for an extensionof indication for the centrally authorised medicine Evoltra (clofarabine). Evoltra was expected to be used for the treatment of acute myeloid leukaemia in ...

Millennium Expands VELCADE(R) (Bortezomib) For Injection Program In Non-Hodgkin’s Lymphoma

Monday, March 17th, 2008

Millennium Pharmaceuticals, Inc. (Nasdaq: MLNM) announced the initiation of a multi-center, Phase II trial to evaluate VELCADE in combination with emerging agent, bendamustine, and current standard of care, rituximab, in patients with relapsed follicular lymphoma, a subset of non-Hodgkin's lymphoma (NHL). This trial is part of the Company's comprehensive development ...

FDA Accepts TREANDA(R) New Drug Application For The Treatment Of Relapsed Indolent Non-Hodgkin’s Lymphoma

Monday, March 17th, 2008

Cephalon, Inc. (Nasdaq: CEPH) announced that the U.S. Food and Drug Administration (FDA) has accepted the company's new drug application (NDA) for TREANDA(R) (bendamustine HCl) for Injection for the treatment of patients with indolent B-cell non-Hodgkin's lymphoma (NHL) who have progressed during or following treatment with rituximab or a rituximab-containing ...

Xencor Initiates Phase I Clinical Trial With XmAb2513 In Lymphoma

Monday, March 17th, 2008

Xencor, Inc., a company developing protein and antibody therapeutics, has initiated a Phase I clinical trial with its lead product candidate XmAb™2513 in patients with Hodgkin lymphoma (HL) and Anaplastic Large Cell Lymphoma (ALCL). XmAb2513 is a humanized monoclonal antibody that targets the antigen CD30. It is engineered to contain ...

Micromet Announces The Publication Of BiTE Antibody Review In Drugs Of The Future

Monday, March 17th, 2008

Micromet, Inc. (Nasdaq: MITI), a biopharmaceutical company developing novel, proprietary antibodies for the treatment of cancer, inflammation and autoimmune diseases, announced the publication of a comprehensive review article entitled, "BiTE: A new class of antibodies that recruit T cells" in the journal Drugs of the Future. BiTE(R) antibodies ...

Discovery That Blood Stem Cells Originate And Are Nurtured In The Placenta May Allow Researchers To Mimic Embryonic Environment

Thursday, March 6th, 2008

Solving a long-standing biological mystery, UCLA stem cell researchers have discovered that blood stem cells, the cells that later differentiate into all the cells in the blood supply, originate and are nurtured in the placenta.The discovery may allow researchers to mimic the specific embryonic microenvironment necessary for development of blood ...

NICE Approves MabThera(R) (Rituximab) As Maintenance Therapy For Patients With Follicular Non-Hodgkin Lymphoma

Thursday, February 28th, 2008

The National Institute for Health and Clinical Excellence (NICE) issued final guidance recommending the use of MabThera(R) (rituximab), as a maintenance therapy for patients with relapsed/refractory follicular non-Hodgkin lymphoma (NHL) responding to induction therapy with chemotherapy with or without rituximab. 1 This is an important breakthrough as it represents a ...